Genome engineering for science and medicine

Our approach

Our scientific interests lie in developing innovative methods in molecular and genetic engineering for applications in regenerative medicine, treating disease, and enhancing our understanding of fundamental biological processes.  Our work in these areas capitalizes on the products of the Genomic Revolution and modern advances in the fields of genome engineering, genetic reprogramming, gene delivery, protein engineering, stem cell transplantation, and synthetic biology to create biologic approaches with the potential to improve human health.

Cellular and molecular engineering of new biological systems

We envision the engineering of a new biology to fulfill previously intractable design criteria for a myriad of solutions to challenges in medicine and science.

 

Commitment to education and outreach

Our intellectual interests are complemented by our dedication to training the next generation of scientists and engineers at the high school, undergraduate, graduate, and postdoctoral level.  

Our Research

  • Genome editing

    Genome engineering for gene and cell therapy

  • Epigenome editing and gene regulation

  • Programming cell biology

  • Genetic control systems

September 16, 2026

Congratulations to Sara for receiving the 2026 IGVF Consortium GPS Team Leadership Award

Arial view of Thessaloniki, Greece.

May 29, 2026

Congratulations to on being selected to give a talk at the annual Research in Computational Molecular Biology conference in Thessaloniki, Greece

Our News

St. Louis, MO skyline at dusk.

September 14, 2026

Congratulations to Alyssa and Boxun on being selected to give flash talks at the annual IGVF consortium meeting in St. Louis, MO

Headshot of Danai.

August 21, 2026

Congratulations to Danai for receiving a Duke School of Medicine Precision Genomics Collaboratory-OBGE graduate student pilot research grant